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Septerna, Inc.

Septerna, Inc. Score & Ratio Trend

DateScoreP/EP/BD/EPrice
Oct 2026 18,231 -67.4 4.39 0.06 3,467.94
Oct 2026 18,246 -67.3 4.38 0.06 3,448.49
Oct 2026 18,066 -69.4 4.52 0.06 3,556.29
Oct 2026 18,242 -67.3 4.39 0.06 3,442.89
Oct 2026 18,237 -67.4 4.39 0.06 3,449.42
Oct 2026 17,761 -72.9 4.75 0.06 3,731.02
Oct 2026 17,536 -75.5 4.92 0.06 3,855.17
Oct 2026 17,517 -75.7 4.93 0.06 3,858.70
Oct 2026 17,592 -74.8 4.88 0.06 3,830.15

Septerna, Inc. Quarterly Results

Line Item Jun 2026Mar 2026Dec 2025Sep 2025
Revenue 26,746,000.0 26,523,000.0 24,118,000.0 21,495,000.0
Net Profit -13,034,000.0 -8,637,000.0 -10,738,000.0 8,173,000.0
EPS -0.3 -0.2 -0.2 0.2

Septerna, Inc. Revenue & Profit: Last 4 Years

Line Item Dec 2025Dec 2024Dec 2023Dec 2022
Revenue 45,951,000.0 1,075,000.0 151,000.0 0.0
Net Profit -48,879,000.0 -71,798,000.0 4,180,000.0 -27,676,000.0
EPS -1.1 -7.3 0.0 -1.4

Septerna, Inc. Balance Sheet

Line Item Dec 2025Dec 2024Dec 2023Dec 2022
Total Assets 596,187,000.0 456,554,000.0 130,867,000.0 36,119,000.0
Total Liabilities 214,261,000.0 36,507,000.0 169,241,000.0 80,320,000.0
Total Equity 381,926,000.0 420,047,000.0 -38,374,000.0 -44,201,000.0

Owes vs Owns

Septerna, Inc. owed $0.32 for every $1 it owned in Jun 2026, down from $2.22 in Dec 2022.

PeriodJun 2026Dec 2025Dec 2024Dec 2023Dec 2022
Owes vs Owns 0.32× 0.36× 0.08× 1.29× 2.22×

Everything the company owes ÷ everything it owns. Below 1× it owns more than it owes; above 1× it owes more than it owns.

Septerna, Inc. Assets & Liabilities Breakdown (USD millions)

What it owns — Dec 2025

Cash & short-term investments 65.6%Receivables 2.3%Fixed assets (tangible) 4.3%Long-term investments 26.4%Other assets 1.3%

How it's funded — Dec 2025

Long-term debt 3.6%Payables 1.7%Other liabilities 30.3%Shareholders' equity 64.1%
Line Item Dec 2025Dec 2024Dec 2023Dec 2022
Assets
Cash & short-term investments391.1350.988.530.6
Receivables13.71.122.80.0
Inventory0.00.00.00.0
Fixed assets (tangible)25.928.717.23.1
Intangible assets0.00.00.00.0
Long-term investments157.669.90.00.0
Other assets7.95.92.42.4
Liabilities & equity
Short-term debt2.21.90.00.7
Long-term debt21.423.612.60.0
Payables10.33.22.63.1
Other liabilities180.47.8154.076.5
Shareholders' equity381.9420.0-38.4-44.2
Net tangible assets381.9420.0-38.4-44.2

Septerna, Inc. Cash Flow

Line Item Dec 2025Dec 2024Dec 2023Dec 2022
Operating Activities 110,189,000.0 -67,470,000.0 -38,723,000.0 -23,303,000.0
Investing Activities -229,352,000.0 -160,598,000.0 22,122,000.0 -1,289,000.0
Financing Activities 1,689,000.0 377,781,000.0 74,520,000.0 30,051,000.0

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