PositoAI/ US/ Septerna, Inc.

Septerna, Inc.

NasdaqGM: SEPN · Healthcare

Positivity Index

#5,399 / 6,774

Global

#2,929 / 4,000

United States

Positivity Score

17,517

Rank→

Overview Go Deep Penta Pattern Funda News For this company Histo

PosiRed: no active red flags

Septerna, Inc. — Overview & Financial Snapshot

Septerna, Inc. (NasdaqGM: SEPN) is a Healthcare company, ranked #5,399 of 6,774 companies globally and #2,929 of 4,000 in United States on PositoAI, with a Positivity Score of 17,517. Its market capitalisation is ₹18,011.22 Cr ($1.91B), P/E ratio is -75.7 and P/B ratio is 4.93. It has no active red flags (PosiRed) or yellow flags (PosiYellow) on record.

For financial statements, ratio trends and score history, Go Deep →

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Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 negative allosteric modulator (NAM) for chronic spontaneous urticaria and other mast cell diseases; and TSHR Program, an oral small molecule TSHR NAM for graves' disease and thyroid eye disease. In addition, it focuses on other therapeutic areas, including neurology, women's health, cardiovascular disease, and respiratory disease. It has global collaboration and license agreement with Novo Nordisk to discover, develop and commercialize multiple potential oral small molecule therapies for metabolic-related diseases based on certain specified molecular targets. The company was formerly known as GPCR NewCo, Inc. and changed its name to Septerna Inc. in June 2021. Septerna, Inc. was incorporated in 2019 and is headquartered in South San Francisco, California.

P/B Ratio 4.93

P/E Ratio -75.7

D/E Ratio 0.06

ROE -6.34%

Owes vs Owns ? 0.32× Low $0.32 owed for every $1 it owns · balance sheet Jun 2026

Dividend Yield 0.00%

Trailing EPS ₹-50.97$-0.54

Forward EPS ₹-183.21$-1.94

Beta —

Market Cap ₹18,011.22 Cr$1.91B

What these numbers mean →

What does Septerna, Inc. do?

What is Septerna, Inc.'s P/E and P/B ratio?

Septerna, Inc. has a P/E ratio of -75.7 and a P/B ratio of 4.93.

What is Septerna, Inc.'s debt-to-equity ratio?

Septerna, Inc. has a debt-to-equity ratio of 0.06.

How much does Septerna, Inc. owe compared with what it owns?

Septerna, Inc. owes $0.32 for every $1 it owns (balance sheet Jun 2026), which is low.

What is Septerna, Inc.'s Positivity rank?

Septerna, Inc. is ranked #5,399 of 6,774 companies globally and #2,929 of 4,000 in United States on PositoAI, with a Positivity Score of 17,517.

Does Septerna, Inc. have any regulatory orders, red flags (PosiRed) or yellow flags (PosiYellow)?

No active red flags (PosiRed) or yellow flags (PosiYellow) are currently on record for Septerna, Inc..

Where can I read the latest news about Septerna, Inc.?

Recent headlines about Septerna, Inc. from the last 30 days, with links to the original articles, are on its News page on PositoAI.

Does Septerna, Inc. have a PositoAI PosiShot or QR code?

Yes. A dated PosiShot of Septerna, Inc.'s current position, a PosiQR code for its live profile and a ready-made dated mention are available on its For this company page on PositoAI.

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