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Spero Therapeutics, Inc.

Spero Therapeutics, Inc. Score & Ratio Trend

DateScoreP/EP/BD/EPrice
Oct 2026 24,296 8.6 1.48 0.05 106.34
Oct 2026 24,273 8.7 1.49 0.05 107.31
Oct 2026 24,342 7.9 1.45 0.05 104.19
Oct 2026 24,296 8.0 1.48 0.05 106.19
Oct 2026 24,067 8.7 1.61 0.05 115.68
Oct 2026 24,182 8.4 1.54 0.05 110.66
Oct 2026 24,273 8.1 1.49 0.05 106.66

Spero Therapeutics, Inc. Quarterly Results

Line Item Jun 2026Mar 2026Dec 2025Sep 2025
Revenue 0.0 258,000.0 39,658,000.0 3,048,000.0
Net Profit -9,552,000.0 -7,203,000.0 31,520,000.0 -7,382,000.0
EPS -0.2 -0.1 0.6 -0.1

Spero Therapeutics, Inc. Revenue & Profit: Last 5 Years

Line Item Dec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Revenue 59,619,000.0 27,396,000.0 96,735,000.0 48,579,000.0 —
Net Profit 8,572,000.0 -68,566,000.0 22,806,000.0 -46,415,000.0 —
EPS 0.1 -1.3 0.4 -1.2 —

Spero Therapeutics, Inc. Balance Sheet

Line Item Dec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Total Assets 68,919,000.0 110,543,000.0 182,390,000.0 124,802,000.0 —
Total Liabilities 9,898,000.0 64,420,000.0 75,496,000.0 48,868,000.0 —
Total Equity 59,021,000.0 46,123,000.0 106,894,000.0 75,934,000.0 —

Owes vs Owns

Spero Therapeutics, Inc. owed $0.16 for every $1 it owned in Jun 2026, down from $0.39 in Dec 2022.

PeriodJun 2026Dec 2025Dec 2024Dec 2023Dec 2022
Owes vs Owns 0.16× 0.14× 0.58× 0.41× 0.39×

Everything the company owes ÷ everything it owns. Below 1× it owns more than it owes; above 1× it owes more than it owns.

Spero Therapeutics, Inc. Assets & Liabilities Breakdown (USD millions)

What it owns — Dec 2025

Cash & short-term investments 58.4%Receivables 36.8%Fixed assets (tangible) 2.1%Other assets 2.6%

How it's funded — Dec 2025

Short-term debt 2.8%Long-term debt 1.4%Payables 1.0%Other liabilities 9.2%Shareholders' equity 85.6%
Line Item Dec 2025Dec 2024Dec 2023Dec 2022
Assets
Cash & short-term investments40.352.976.3109.1
Receivables25.452.550.71.1
Inventory0.00.00.00.0
Fixed assets (tangible)1.53.14.25.5
Intangible assets0.00.00.00.0
Long-term investments0.00.00.00.0
Other assets1.82.151.29.1
Liabilities & equity
Short-term debt2.01.71.71.7
Long-term debt0.92.63.85.0
Payables0.77.31.40.6
Other liabilities6.352.868.641.6
Shareholders' equity59.046.1106.975.9
Net tangible assets59.046.1106.975.9

Spero Therapeutics, Inc. Cash Flow

Line Item Dec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Operating Activities -12,624,000.0 -23,444,000.0 -32,995,000.0 -7,731,000.0 —
Investing Activities — — 0.0 33,807,000.0 7,672,000.0
Financing Activities — 0.0 221,000.0 -29,553,000.0 84,050,000.0

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