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Protagonist Therapeutics, Inc.

PosiFunda Ratios Only on PositoAI

PositoAI's own ratios from Protagonist Therapeutics, Inc.'s yearly results (2022–2025), compared with Healthcare companies in United States. Tap ? on any ratio for what it means.

What stands out

  • Self-Funding Ratio: Over the last 3 years its own operating cash covered its investment spending (capex) 48.3 times. Higher than almost all Healthcare companies in United States.
  • Debt Due Cover Ratio: Debt due within a year is covered 25.3 times by its yearly operating cash. Higher than 91% of Healthcare companies in United States.
  • Profit Cash Ratio: Over the last 3 years, every $100 of reported profit came with $260 of operating cash. Higher than 85% of Healthcare companies in United States.

Cash quality

Profit Cash Ratio

$260

Over the last 3 years, every $100 of reported profit came with $260 of operating cash.

Higher than 85% of Healthcare companies in United States.

Self-Funding Ratio

48.3×

Over the last 3 years its own operating cash covered its investment spending (capex) 48.3 times.

Higher than almost all Healthcare companies in United States.

Cash Locked Ratio

—

Data incomplete

Growth quality

Steadiness Ratio

2/3 · 2/3

Sales grew in 2 of the last 3 years; profit grew in 2 of 3.

Steadier than 69% of Healthcare companies in United States.

Growth Efficiency Ratio

−$14

Sales grew 73% in 3 years, but profit fell: $14 less profit per $100 of extra sales.

Lower than 75% of Healthcare companies in United States.

Asset Productivity Ratio

+73% / +170%

In 3 years sales changed by +73% while total assets changed by +170%. Assets grew faster than sales.

Balance-sheet strength

Debt Due Cover Ratio

25.3×

Debt due within a year is covered 25.3 times by its yearly operating cash.

Higher than 91% of Healthcare companies in United States.

Cash Cushion Ratio

+6%

Cash, after subtracting all debt, equals 6% of its market value (net cash).

Lower than 55% of Healthcare companies in United States.

Tangible Assets Ratio

—

Data incomplete

Tangible Net Worth Ratio

—

Data incomplete

Shareholders

Shareholder Slice Ratio

+27%

Share count rose 27% in 3 years, so each share's slice of the company became smaller.

Smaller rise in share count than 54% of Healthcare companies in United States.

Standard fundamentals

P/E, P/B, ROE, debt, growth and more (12)

Protagonist Therapeutics, Inc. owes $0.05 for every $1 it owns. Protagonist Therapeutics, Inc. made a loss in the year to Dec 2025, after a profit the year before.

Compared with Healthcare companies in United States · latest annual results Dec 2025.

P/E ratio

135.5

Investors pay $135.5 for every $1 of Protagonist Therapeutics, Inc.'s yearly profit, higher than 93% of Healthcare companies in United States.

P/B ratio

10.73

The share price is 10.73 times Protagonist Therapeutics, Inc.'s book value per share, higher than 87% of Healthcare companies in United States.

Market cap

$9.0 B

The total market value of all of Protagonist Therapeutics, Inc.'s shares at today's price (share price × number of shares), larger than 89% of Healthcare companies in United States. PosiCap size class: Meso Cap.

Net worth (book value)

$842 M

What Protagonist Therapeutics, Inc. would have left on paper if it sold everything it owns and paid everything it owes, from its latest balance sheet (30 Jun 2026).

Book value per share

$13.01

Net worth divided by the number of shares. The share price of $139.53 is 10.7 times this, which is the P/B above.

Return on equity (ROE)

11.0%

Protagonist Therapeutics, Inc. earned 11.0% on its shareholders' money over the last year, higher than 84% of Healthcare companies in United States.

Owes vs Owns

0.05×

Protagonist Therapeutics, Inc. owes $0.05 for every $1 it owns (low), lower than 97% of Healthcare companies in United States.

Dividend yield

None

Protagonist Therapeutics, Inc. does not currently pay a dividend.

Revenue growth

-89%

Revenue fell 89% in the year to Dec 2025, and grew 20% a year on average over 3 years.

Profit growth

Loss

Protagonist Therapeutics, Inc. made a loss in the year to Dec 2025, after a profit the year before.

Profit margin

-282.8%

Protagonist Therapeutics, Inc. lost $283 for every $100 of revenue.

Cash vs debt

Net cash

Protagonist Therapeutics, Inc. held $557 M more cash than debt (net cash) at Dec 2025.

Questions

What is Protagonist Therapeutics, Inc.'s P/E ratio?

Investors pay $135.5 for every $1 of Protagonist Therapeutics, Inc.'s yearly profit, higher than 93% of Healthcare companies in United States.

How is P/B calculated on PositoAI?

P/B is market cap divided by net worth from the latest balance sheet. For Protagonist Therapeutics, Inc.: $9.0 B ÷ $842 M (30 Jun 2026) = 10.7.

What is Protagonist Therapeutics, Inc.'s return on equity?

Protagonist Therapeutics, Inc. earned 11.0% on its shareholders' money over the last year, higher than 84% of Healthcare companies in United States.

How much does Protagonist Therapeutics, Inc. owe compared with what it owns?

Protagonist Therapeutics, Inc. owes $0.05 for every $1 it owns (low), lower than 97% of Healthcare companies in United States.

Does Protagonist Therapeutics, Inc. pay a dividend?

No. Protagonist Therapeutics, Inc. does not currently pay a dividend.

Is Protagonist Therapeutics, Inc.'s revenue growing?

Revenue fell 89% in the year to Dec 2025, and grew 20% a year on average over 3 years.

Figures from the company's yearly results and PositoAI's own data. Full tables are on the Go Deep tab. What each figure means. PositoAI is for research and education only and is not investment advice.

Disclaimer — PositoAI is a research and screening tool for educational and informational purposes. It is not investment advice or a recommendation to buy or sell any security or mutual fund. Scores and rankings are calculated by PositoAI's own method using publicly available data, which may be incomplete, delayed or inaccurate, and past performance does not indicate future results. AI summaries of company news may contain errors. PositoAI is not registered with the SEC, SEBI or any other regulatory authority. Please do your own research or consult a licensed financial advisor before investing.